Symbol
Name
ID

Ccr5
C-C motif chemokine receptor 5
MGI:107182

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Retinal hemorrhage

Diffuse alveolar hemorrhage

Localized pulmonary hemorrhage

Anemia

Hemolytic anemia

Eosinophilia

Increased T cell count

Leukopenia

Granulomatosis

Superficial thrombophlebitis

Thrombocytopenia

Elevated erythrocyte sedimentation rate

Disease(s) Associated with CCR5

Behcet's disease

granulomatosis with polyangiitis

rheumatoid arthritis

sarcoidosis

Mouse Phenotypes

abnormal Kupffer cell morphology

impaired macrophage chemotaxis

abnormal cellular extravasation

abnormal leukocyte adhesion

decreased T cell proliferation

decreased NK cell number

increased NK T cell number

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD8-positive, alpha beta T cell morphology

abnormal leukocyte physiology

increased IgG1 level

abnormal NK T cell physiology

decreased microglial cell activation

Availability

Mouse Genotype

Ccr5^tm1Blck/Ccr5^tm1Blck

Ccr5^tm1Brv/Ccr5^tm1Brv

Ccr5^tm1Kuz/Ccr5^tm1Kuz

Ccr5^tm1Sush/Ccr5^tm1Sush

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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